vicissitude

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• March 4. 2016 from wordnet.princeton.edu

  vicissitude — noun — english

  a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research"

• March 4. 2016 from wordnet.princeton.edu

  vicissitude — noun — english

  mutability in life or nature (especially successive alternation from one condition to another)